Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.rights.licenseReconocimiento-NoComercial 4.0 Internacional. (CC BY-NC)-
dc.contributor.authorPérez Barthaburu, M. E.es
dc.contributor.authorKeuchkerian, R.es
dc.contributor.authorSuescun, L.es
dc.contributor.authorCrisci, C.es
dc.contributor.authorAguiar, I.es
dc.contributor.authorMartínez Lopéz, W.es
dc.contributor.authorRodriguez Chialanza , M.es
dc.date.accessioned2024-08-22T17:10:06Z-
dc.date.available2024-08-22T17:10:06Z-
dc.date.issued2022-
dc.identifier.urihttps://hdl.handle.net/20.500.12381/3591-
dc.description.abstractUpconverting nanoparticles (UCNps) possess the ability to convert light from low to high energy. In particular, the absorption of radiation by these nanomaterials in the near-infrared region of the spectrum, and their subsequent emission in the visible region, is of great interest for biomedical applications. Conventional antitumor therapies often produce a high degree of side effects. Consequently, it is proposed to investigate the development of less invasive alternative therapies as photothermal therapy, using UCNps. The upconversion property could be achieved by incorporating dopants (rare earths and transition metals) in fluorine-based crystalline environments. On the other hand, it is important to control the size of the nanoparticles for their use in biomedical applications, for that reason we plan to obtain nanoparticles with an approximate size less than 50 nm. In the present work, the development of KMgF3 fluoroperovskite nanoparticles by solvothermal synthesis is presented, applying a factorial experimental design which consists of four factors (temperature, time and two limiting reagents) at two levels and choosing the average particle size as a variable response. The samples were characterized by powder X-ray diffraction and Transmission Electron Microscopy, in order to know the crystalline phase and particle size. As a result, KMgF3 nanoparticles with an average size between 13 and 31 nm were obtained. In addition, data obtained were statistically processed by Analysis of Variance, to determine the significant factors and their interactions, achieving the optimal synthesis conditions. From these results, a series of samples doped with Mn2+ and/or Nd3+ were obtained in order to find the optimal dopant concentrations for efficient upconversion properties. Our work is the starting point for the development of UCNps allowing them to be applied in future antitumor therapies.es
dc.description.sponsorshipAgencia Nacional de investigación e Innovaciónes
dc.description.sponsorshipPrograma de Desarrollo de las Ciencias Básicases
dc.description.sponsorshipComisión Académica de Postgradoes
dc.language.isoenges
dc.rightsAcceso abierto*
dc.sourceXX B-MRS Meeting. Foz do Iguaçu-PR, 25-29 September 2022es
dc.subjectExperimental designes
dc.subjectNano-fluoroperovskitaes
dc.subjectPhotodynamic Therapyes
dc.titleFluoro-perovskite nanomaterials for photodynamic cancer treatment”es
dc.typeDocumento de conferenciaes
dc.subject.aniiIngeniería y Tecnología
dc.subject.aniiNanotecnología
dc.subject.aniiNano-materiales
dc.identifier.aniiFCE_3_2020_1_162287es
dc.type.versionPublicadoes
dc.anii.institucionresponsableUniversidad de la Repúblicaes
dc.anii.subjectcompleto//Ingeniería y Tecnología/Nanotecnología/Nano-materialeses
Aparece en las colecciones: Publicaciones de ANII

Archivos en este ítem:
archivo  Descripción Tamaño Formato
Presentacion_SBPMat2022.pdfDescargar 6.59 MBAdobe PDF

Las obras en REDI están protegidas por licencias Creative Commons.
Por más información sobre los términos de esta publicación, visita: Reconocimiento-NoComercial 4.0 Internacional. (CC BY-NC)